General Cell Lines and Cell Cultures
ORGANABIO LLC Human Autoimmune Peripheral Blood Mononuclear Cells (PBMCs) / Cryopreserved / Single Donor / 5x10E7 cells/vial / OrganaBio LEUKOPAC - PBMC (Lupus / UC / Celiac / Crohn / RA) / Research Use Only
Human peripheral blood PBMCs from recallable autoimmune donors (SLE / Lupus / Crohn / UC / Celiac / RA / etc). Cryopreserved characterized with immunophenotyping (CD45 / CD14 / CD19 / CD56 / CD3 / CD3CD4 / CD3CD8) / infectious disease testing / and HLA typing. Available in 1x10E7 and 5x10E7 cell vials. OrganaBio Human disease state PBMCs are isolated from peripheral blood of autoimmune donors. Each lot is cryopreserved and characterized by immunophenotyping. Includes infectious disease testing and HLA typing with full donor demographics. Ideal for autoimmune disease research / target validation / and drug development studies.
Biochain Institute Inc Paraffin Tissue Section - Human Appendix Tumor, 5 sides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from a single human tumor. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
ATCC Septoria tritici
An ampoule containing viable cells (yeast cells, spores, or agar cubes with mycelia) suspended in cryoprotectant.
Amsbio LLC eLuCidate™ HEK 293, TLR5/NF-kB Reporter Cell Line
eLuCidate™ HEK 293 TLR5/NF-kB Reporter Cell Line
Genscript Corporation CD47 Fc Chimera Human
Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3 Integrin-associated protein (IAP) and Protein MER6 CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain CD47 is a 40 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily and an integral membrane protein that consists of a 123 amino acid (aa) extracellular domain (ECD) with a single Ig-like domain five membrane-spanning regions with short intervening loops and a 34 aa C-terminal cytoplasmic tail CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity CD47 is the receptor for SIRPA binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells CD47 Interaction with SIRPG mediates cell-cell adhesion enhances superantigen-
Eurofins Discoverx cAMP Hunter CHO-K1 HTR5A Gi Cell Line, 2 vials. (95-0160C2)
The cAMP Hunter HTR5A Gi cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. serotonin/5-HT) based activation of HTR5A GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type HTR5A, a naturally Gi/Go coupled GPCR. Upon activation of HTR5A, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx ChemiScreen AT2 Angiotensin II Receptor Membrane Preparation, 1 vial. (HTS208M)
The ChemiScreen AT2 Angiotensin II Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of AGTR2 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx PathHunter MC3R Total Internalization U2OS Cell Line, 2 vials. (93-0837C3)
The PathHunter MC3R Total Internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of MC3R via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged MC3R and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the MC3R receptor to the early endosome leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
![ATCC Vaccinia virus; Strain: vTF7-3 [Wr]](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502384147.PNG-250.jpg)
ATCC Vaccinia virus; Strain: vTF7-3 [Wr]
Vaccinia virus strain vTF7-3 [Wr] is propagated in BS-C-1 cells (ATCC CCL-26). This strain was constructed in vitro by transfecting vaccinia virus-infected cells with pTF703 cells (ATCC 67202) and was deposited by the National Institutes of Health. It expresses bacteriophage T[7] RNA polymerase. This product requires a VS 16-6A permit, which can be downloaded at the USDA website here. Please submit the completed permit form to SalesPermits@atcc.org with your ATCC sales order number and/or your purchase number noted in the subject line and body of the email.
ABclonal Technology NPSR1 Rabbit pAb
This gene encodes a member of the vasopressin/oxytocin subfamily of G protein-coupled receptors. The encoded membrane protein acts as a receptor for neuropeptide S and affects a variety of cellular processes through its signaling. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Polymorphisms in this gene have also been associated with asthma susceptibility, panic disorders, inflammatory bowel disease, and rheumatoid arthritis. Alternative splicing results in multiple transcript variants.
Meso Scale Discovery U-PLEX Human ICOS-L/B7-H2 ASY
The Meso Scale Discovery U-PLEX Human ICOS/L B7-H2 Assay is a multiplex immunoassay kit that enables simultaneous quantitative measurement of human Inducible T cell COStimulator (ICOS) and B7 Homolog 2 (B7-H2) biomarkers in serum plasma and cell culture supernatants This electrochemiluminescent assay utilizes MSD s proprietary SECTOR Imager 6000 for high sensitivity and broad dynamic range The kit includes a 96-well plate pre-coated with capture antibodies detection antibodies Read Buffer Diluent 2 Calibrator Blend and Wash Buffer This assay provides reproducible and sensitive detection of human ICOS and B7-H2 with a minimal sample volume requirement of 25 L
Eurofins Discoverx PathHunter U2OS TSHR (Long Isoform) β-Arrestin Cell Line, 2 vials. (93-0760C3)
The PathHunter TSHR(L) cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. TSH) based activation of TSHR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged TSHR and EA-tagged β-Arrestin-2. Activation of TSHR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.